Novel Approaches to NMR and MRI

We have a long-standing focus on the development of novel approaches to NMR and MRI, as well as application of these techniques in both the physical and life sciences.  Our current research activities include the development of an open-access, low-magnetic-field human MRI instrument, and its application to studies of: (i) traumatic brain injury (TBI); (ii) molecular imaging using hyperpolarized nanoparticles and other media created by dynamic nuclear polarization (DNP); and (iii) pulmonary physiology using inhaled hyperpolarized noble gas (3He and 129Xe).  We are also investigating the creation and application of novel spin states in biomolecules, such as long-lived nuclear spin singlet states and coherences between singlet and triplet states.

Our NMR and MRI investigations are performed in the Walsworth Lab at the Center for Astrophysics and the Low-Field Imaging (LFI) Lab at the Martinos Center for Biomedical Imaging.